The Los Angeles Post

AstraZeneca antibody cocktail considered effective in preventing symptomatic COVID-19 among the high-risk

by · Published · Updated

AstraZeneca scored a win on Friday as data showed its antibody cocktail is 77 percent effective at preventing symptomatic COVID-19 in high-risk populations.

The research found no one who took AstraZeneca’s combination, called AZD7442, developed severe COVID-19 or died due to the virus. In comparison, three participants who received the placebo endured serious illness, with two fatalities.

AstraZencea called the treatment, involving the antibodies ixagevimab and cilgavimab, the first “long-acting antibody combination to prevent COVID-19” in a release.

Overall, 25 positive coronavirus infections were confirmed in the Provent study involving more than 5,100 patients across sites in the ​​U.S., U.K., Belgium, France and Spain. The participants were unvaccinated at the time and had a negative test.

Significance: Drug manufacturers have been testing different antibody treatments for COVID-19 to provide a way to help those who may not have adequate vaccine protection, including cancer patients, fight the virus.

“With these exciting results, AZD7442 could be an important tool in our arsenal to help people who may need more than a vaccine to return to their normal lives,” Myron Levin, principal investigator in the study, said in a statement.

What’s next: The study is expected to be sent to a peer-reviewed medical journal to be published, as well as to regulators for an emergency use authorization or conditional approval.